Calcitonin is a hormone produced by the thyroid gland which is taken by some patients to treat osteoporosis. New research suggests that calcitonin may have a condroprotective effect (Chondrocytes are cells found in cartilage) in addition to the well-established effect on bone resorption (Karsdal et al, 2006).
"By improving functional disability and by reducing levels of biomarkers that are thought to be predictive of joint space narrowing (and thus cartilage loss), oral sCT at a dose of 1 mg might be a useful pharmacologic agent in human knee OA" Manicourt et al, 2006).
*Please refer to the disclaimer text.
Karsdal MA, Tanko LB, Riis BJ, Sondergard BC, Henriksen K, Altman RD, Qvist P, Christiansen C. Calcitonin is involved in cartilage homeostasis: is calcitonin a treatment for OA? Osteoarthritis Cartilage. 2006 Jul;14(7):617-24. Epub 2006 May 12.
Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP. Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. 1: Arthritis Rheum. 2006 Oct;54(10):3205-11.
"By improving functional disability and by reducing levels of biomarkers that are thought to be predictive of joint space narrowing (and thus cartilage loss), oral sCT at a dose of 1 mg might be a useful pharmacologic agent in human knee OA" Manicourt et al, 2006).
*Please refer to the disclaimer text.
Karsdal MA, Tanko LB, Riis BJ, Sondergard BC, Henriksen K, Altman RD, Qvist P, Christiansen C. Calcitonin is involved in cartilage homeostasis: is calcitonin a treatment for OA? Osteoarthritis Cartilage. 2006 Jul;14(7):617-24. Epub 2006 May 12.
Manicourt DH, Azria M, Mindeholm L, Thonar EJ, Devogelaer JP. Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. 1: Arthritis Rheum. 2006 Oct;54(10):3205-11.
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